BoltzGen

MIT Unveils BoltzGen: A Generative AI for Designing Therapeutic Molecules In a major leap for drug discovery, scientists at MIT have introduced BoltzGen, a generative AI model capable of creating novel protein binders from scratch. This innovative tool is designed to address diseases that have long been considered difficult or impossible to treat, marking a significant shift from predictive biology to generative engineering in medicine. How BoltzGen Unifies Design and Prediction BoltzGen stands out by unifying protein design and structure prediction into a single, powerful process. The model incorporates specific constraints to ensure that the molecules it generates are not only novel but also functional and stable, adhering to the fundamental laws of physics and chemistry. Unlike previous models that were often limited to specific protein types, BoltzGen is engineered as a more general-purpose tool, capable of creating a much wider range of therapeutic molecules. ...

Anthropic Unveils Claude Opus 4.5, Setting New AI Benchmarks Anthropic has launched Claude Opus 4.5, its most advanced and powerful AI model to date. Now accessible via the Anthropic API and major cloud platforms, Opus 4.5 reportedly establishes a new industry standard for complex tasks, including coding, AI agent development, and multi-step computer operations. The model also demonstrates significantly improved performance in everyday business functions like in-depth research and processing documents such as spreadsheets and presentations. Anthropic is positioning this release for enterprise and engineering teams managing sophisticated projects. Claude Opus 4.5 is available on AWS Bedrock, Google Cloud’s Vertex AI, and Microsoft’s Foundry. ...